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Toradol

This medication includes the active ingredient ketorolac trometamol, which is a type of medication called a non-steroidal anti-inflammatory drug (NSAID).   Ketorolac performs by blocking the action of a material in the body known as cyclo-oxygenase. Cyclo-oxygenase is involved in the creation of a number of chemicals in the body, some of which are known as prostaglandins. Prostaglandins are produced in response to injury or particular diseases and would otherwise go on to cause pain, swelling and inflammation. Ketorolac is therefore taken to relieve pain and inflammation.

All the medications in this group (NSAIDs) reduce inflammation produced by the bodies own immune system, and are successful pain killers. Ketorolac is taken for the temporary relief of moderate to acute pain following surgical operations. It can be administered as an injection for as long as two days and then as tablets for up to seven days.

What is it Toradol used for?

  • Moderate to severe pain following surgery

Toradol Warning!

  • Individuals with weakened kidney function should have their kidney performance observed while taking this medication.
  • This medicine may cause various side effects that could impair your mental or physical ability to safely drive or operate machinery. You should be aware of how you react to this medicine before driving or operating machinery.
  • This medicine is not recommended for women who are trying to get pregnant or who are having difficulty conceiving.

Toradol should be used with caution in

  • Decreased kidney function
  • Decreased liver function
  • Diseases of the stomach and intestines
  • Elderly people
  • Heart failure
  • High blood pressure (hypertension)
  • History of allergies
  • Weak or debilitated people

Not to be used in

  • Allergy to aspirin or other medicines in this class (NSAIDs)
  • Breastfeeding
  • Breathing difficulties due to a narrowing of the airways (bronchospasm)
  • Children under 16 years of age
  • Confirmed or suspected bleeding from the blood vessels in and around the brain
  • Dehydration
  • Growths into the nose (nasal polyps)
  • History of asthma
  • History of bleeding from the stomach or intestines
  • History of peptic ulcers
  • Individuals about to undergo surgery
  • Low volume of circulating blood (hypovolaemia)
  • Moderate to severely decreased kidney function
  • People at increased risk of bleeding
  • People taking medicine to prevent blood clotting (anticoagulants, eg warfarin)
  • People who have had operations with a high risk of bleeding
  • Pregnancy or labor
  • Swelling of the lips, eyes or tongue (angioedema)

This medicine should not be used if you are allergic to one or any of its ingredients. Please inform your doctor or pharmacist if you have previously experienced such an allergy.

If you feel you have experienced an allergic reaction, stop using this medicine and inform your doctor or pharmacist immediately.

Pregnancy and Breastfeeding

Certain medications should not be used during pregnancy or breastfeeding. However, other medications could be securely taken in pregnancy or breastfeeding if the benefits to the mother outweigh the risks to the unborn baby. Always notify your physician if you are pregnant or planning a pregnancy, prior to taking any medication.

  • The safety of this medication during pregnancy has not been determined. For this reason it should not be used during pregnancy, labor or delivery. Seek medical advice from your physician.
  • This medication may distribute into breast milk. Breastfeeding mothers should not take it. Seek medical guidance from your physician.

Label warnings

  • Refer to the written instructions for maximum daily intake.
  • Take this medication with or after food.

Side effects

Medications and their potential side effects can influence individuals in different ways. The following are a number of the side effects that are known to be associated with this medicine. If a side effect is stated here, it does not signify that all individuals taking this medication will experience that or any side effect.

  • Headache
  • Difficulty in sleeping (insomnia)
  • Depression
  • Drowsiness
  • Sweating
  • Trouble of the gut such as diarrhea, constipation, nausea, vomiting or abdominal pain
  • Inflammation of the pancreas (pancreatitis)
  • Indigestion (dyspepsia)
  • Balance problems involving the inner ear (vertigo)
  • Dizziness
  • Excessive fluid retention in the body tissues, resulting in swelling (oedema)
  • Difficulty in breathing (dyspnoea)
  • High blood pressure (hypertension)
  • Skin reactions such as rash and itch
  • Anxiety
  • Increased bleeding time
  • Ulceration or bleeding of the stomach or intestines
  • Kidney disorders
  • Infertility in women
  • Wound bleeding

The side effects listed above may not include all of the side effects reported by the drug's manufacturer.

For additional information concerning any other possible risks connected with this medication, please read the information provided with the medication or consult your physician or pharmacist.

How can this medication affect other medicines?

You should inform your physician or pharmacist about the medications you are taking, particularly those noted below, prior to starting treatment with this medication. This includes those bought without a prescription and herbal medications. All the same, check with your physician or pharmacist prior to starting any new medications while you are using this medicine.

This medication should not be used in combination with any of the following medications:
- aspirin or other non-steroidal anti-inflammatory drugs (NSAIDs), eg ibuprofen, diclofenac
- medicines to prevent blood clotting (anticoagulants), eg warfarin, heparin
- lithium
- probenecid
- pentoxifylline (oxpentifylline).

There could be an elevated risk of side effects on the kidneys if this medicine is taken with any of the following medicines:
- ACE inhibitors, eg captopril, enalapril
- ciclosporin.

This medication could reduce the success of diuretics such as furosemide at treating fluid retention and high blood pressure.

This medication should be used with care in individuals taking methotrexate, as it may increase the blood level of methotrexate and hence the risk of side effects.