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SSRI Antidepressants

Selective Serotonin Reuptake Inhibitors Increase Suicide Risk

Suicidal behavior & SSRI-type antidepressants study shows a 400% increase in unsuccessful suicid attempts in the second week of treatment with two SSRIs - Prozac and Paxil. Suicide attempts risk in the first month of SSRI treatment are up to three times normal in the 2nd through 4th weeks.

Risk of successful suicides are 38 times higher during the first nine days of treatment. Recent studies link SSRI antidepressants to increased suicide risks in teens and some adults. The FDA recently warned doctors prescribing any antidepressant drugs, including SSRI's, to monitor patients being treated with SSRI antidepressants for suicidal behavior.

In the July 21 Journal of the American Medical Association co-author James A. Kaye, MD, DrPH., senior epidemiologist for the Boston Collaborative Drug surveillance program and associate professor at the Boston University School of Public Health. "Yet the time period after starting any of these treatments is a high-risk period. We agree that there should be careful monitoring of patients who have started on these drugs, as the FDA has already advised."

"SSRIs do cause side effects. It remains the case that some people may react badly," Wessely warns. "There may still be an indirect link between SSRIs and suicide. For example, take the SSRI side effects of weight gain and agitation, seen in some people. Such side effects may further disturb patients and increase their risk of suicide.

The following is a list of SSRI's:

Aropax (Generic: Paroxetine), Celexa, Cipramil, Emocal, Effexor Generic: Venlafaxine, Fevarin (Generic: Fluvoxamine), Fontex (Generic: Fluoxetine), Luvox, Lexapro (Generic: Escitalopram), Opitar, Paxil, Prozac, Seromex, Seroni, Seroxat    Sepram (Generic: Citalopram), Wellburtin (Generic: Bupropion), Zoloft (Generic: Sertroline)