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If Sporanox is taken with certain other medications, the effects of both could be amplified, decreased, or altered. It is particularly important to check with your physician before combining Sporanox with any of the following:

Acid-blocking drugs such as Tagamet, Pepcid, and Zantac
Alprazolam (Xanax)
Atorvastatin (Lipitor)
Blood-thinning drugs such as Coumadin
Buspirone (BuSpar)
Busulfan (Myleran)
Calcium channel blockers such as Cardene, Norvasc, and Procardia
Carbamazepine (Tegretol)
Clarithromycin (Biaxin)
Cyclosporine (Sandimmune, Neoral)
Diazepam (Valium)
Dofetilide (Tikosyn)
Digoxin (Lanoxin)
Docetaxel (Taxotere)
Erythromycin (E-Mycin, Ery-Tab, and others)
Indinavir (Crixivan)
Lovastatin (Mevacor)
Methylprednisolone (Medrol)
Midazolam (Versed)
Nevirapine (Viramune)
Oral diabetes medications such as DiaBeta, Diabinese, Glucotrol, Micronase, Orinase, and Tolinase
Phenytoin (Dilantin)
Pimozide (Orap)
Quinidine (Quinidex)
Rifabutin (Mycobutin)
Rifampin (Rifadin, Rimactane)
Ritonavir (Norvir)
Saquinavir (Invirase)
Simvastatin (Zocor)
Sirolimus (Rapamune)
Tacrolimus (Prograf)
Triazolam (Halcion)
Trimetrexate (Neutrexin)
Vinblastine (Velban)