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Etodolac (ee-TOE-doe-lak) Cares for pain produced by arthritis and other medical problems.   Lodine belongs to a class of drugs known as non-steroidal anti-inflammatory drugs (NSAIDs).

You should not take this medication if you have had an allergic reaction to etodolac, aspirin, or other pain and arthritis medicines, such as Motrin®, Naprosyn® or Aleve®, Indocin®, or Clinoril®. The response may have included wheezing or feeling short of breath, hives, rash, or swelling in the face.

How Should You Take Lodine

  • Lodine is available in capsule, tablet and as a long acting tablet
  • Your physician will inform you how much to take and how often.
  • Be sure to take with a full glass of water.
  • You may take the medication with food or antacids (such as Maalox® or Mylanta®) so as to not upset your stomach.
  • Be sure to swallow the capsule and extended-release tablet (Lodine XL®) whole. Do not crush, break, or chew.

If a dose is missed:

  • Take the missed dose as soon as possible.
  • If it is almost time for your next regular dose, wait until then to take your medication and skip the missed dose.
  • You should not use two doses at the same time.

What To Avoid While Using Lodine (Oral)

  • Speak with your physician or pharmacist prior to using any other medications, including over-the-counter medicines, vitamins, and herbal products.
  • You should not use this medication with aspirin or products that contain aspirin, naproxen (Aleve®), or ibuprofen (Advil® or Motrin®).
  • Avoid consuming alcohol while you are taking this medicine.
  • Be sure your physician knows if you are taking Coumadin®.
  • Speak with your physician prior to taking etodolac if you are pregnant or breastfeeding or have heart disease, high blood pressure, blood disorders, liver or kidney disease, or ulcers or other stomach problems. This medication should not be taken during the last 3 months of a pregnancy.
  • This type of medication sometimes causes ulcers and stomach bleeding. These problems can occur without warning signs. You may need to see your physician for regular check-ups while being treated with this medicine.

Lodine Side Effects

Contact your physician immediately if you experience any of these side effects:

  • Severe rash, itching, or hives
  • Rapid swelling in the face or around the eyes
  • Chest tightness, wheezing or trouble breathing
  • Severe stomach pain or bloody vomit
  • Black, tarry, or bloody stools
  • Decrease amount of urine
  • Unusual bruising or bleeding
  • Yellowing of skin or eyes If you notice these less serious side effects, talk with your doctor:
  • Mild nausea or vomiting
  • Gas, indigestion or mild stomach pain
  • Diarrhea or constipation
  • Ringing in the ears
  • Blurred vision
  • Weight gain or swelling of feet or legs
  • Dizziness
  • Sensitivity of skin to sunlight