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Etodolac is a nonsteroidal anti-inflammatory drug (NSAID) useful for treating fever, pain, and inflammation in the body. As a unit, NSAIDs are non-narcotic relievers of mild to moderate pain of many sources, including injury, menstrual cramps, arthritis, and other musculoskeletal conditions. While the response to different NSAIDs differs from patient to patient, it is not uncommon for a physician to try another NSAIDs for any given condition.

Etodolac is administered for the treatment of inflammation and pain brought on by osteoarthritis and rheumatoid arthritis, as well as, soft tissue injuries, such as tendinitis and bursitis. Etodolac is also administered for rapid relief of mild to moderate pain, such as with menstrual cramps.

Etodolac should be taken with food.

Etodolac should be avoided by individuals with a history of asthma attacks, hives, or other allergic reactions to aspirin or other NSAIDs. Unusual, but severe, allergic results have been reported in such patients. Individuals with peptic ulcer disease or poor kidney function also should avoid it, since this medication could worsen both conditions. Etodolac is normally used with caution in individuals taking blood-thinning medications (anticoagulants), such as warfarin (Coumadin), because of increased risk of bleeding. Individuals consuming lithium could develop toxic blood lithium levels. Individuals also taking cyclosporine (Sandimmune) can develop kidney toxicity. Treatment in children has not been sufficiently studied. Etodolac is not habit forming. NSAIDs should be stopped prior to voluntary surgery because of the mild interference with clotting that is characteristic of this group of medicines. Etodolac is best discontinued at least four days in advance of the procedure.