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Anaprox and Naprelan are nonsteroidal anti-inflammatory medications used to reduce mild to moderate pain and menstrual cramps. They are also given for relief of the inflammation, swelling, stiffness, and joint pain connected with rheumatoid arthritis and osteoarthritis (the most common form of arthritis), and for ankylosing spondylitis (spinal arthritis), tendinitis, bursitis, acute gout, and other conditions. Anaprox also may be prescribed for adolescent arthritis.

If you are taking these medications, you should have frequent checkups with your physician if you take Anaprox on a regular basis. Ulcers or internal bleeding can occur without warning.

Your physician may request you to take Anaprox with food or an antacid to prevent an stomach upset. Take Anaprox with a full glass of water.

Take this medication exactly as prescribed by your physician.

If you are using Anaprox for arthritis, it should be taken on a regular basis.

--If you miss a dose...

Anaprox: Take the forgotten dose as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Never take 2 doses at the same time.

Naprelan: Take the forgotten dose only if you remember within 2 hours after the appointed time. Otherwise, skip the dose and go back to your regular schedule.

Side effects cannot be predicted. If any develop or change in strength, notify your physician as soon as possible. Only your physician can establish if it is safe for you to resume taking Anaprox.

  • Further common side effects of Anaprox may include:
    Abdominal pain, bruising, constipation, diarrhea, strenuous or labored breathing, dizziness, drowsiness, headache, hearing disturbances, heartburn, indigestion, inflammation of the mouth, itching, light-headedness, nausea, rapid, fluttery heartbeat, red or purple spots on the skin, ringing in the ears, skin eruptions, sweating, swelling due to fluid retention, thirst, vertigo, vision changes
  • Less common or rare side effects of Anaprox may include :
    Abdominal bleeding, black stools, blood in the urine, change in dream patterns, chills and fever, colitis (inflammation of the large intestine), congestive heart failure, depression, general feeling of illness, hair loss, inability to concentrate, inability to sleep, inflammation of the lungs, kidney disease or failure, menstrual problems, muscle weakness and/or pain, peptic ulcer, severe allergic reactions, skin inflammation due to sensitivity to light, skin rashes, vomiting, vomiting blood, yellow skin and eyes

If you are vulnerable to or have ever had an allergic response to Anaprox, aspirin, or similar drugs such as Motrin, if you have had asthma attacks caused by aspirin or other drugs of this type, or if you have ever retained fluid or had hives or nasal tumors, you should not take this medication. Make sure your physician is notified of any drug reactions you have experienced.

Keep in mind that peptic ulcers and bleeding can occur without warning.

This drug should be used with caution if you have kidney or liver disease. It can cause liver inflammation in some people.

Do not take aspirin or any other anti-inflammatory medications while taking Anaprox, unless your doctor tells you to do so.

Anaprox and Naprelan contain sodium. If you are on a low sodium diet, discuss this with your doctor.

Use with caution if you have heart disease or high blood pressure. This drug can increase water retention. It also may cause vision problems. If you experience any changes in your vision, inform your doctor.

This drug makes some people drowsy or less alert. Avoid driving, operating dangerous machinery, or participating in any hazardous activity that requires full mental alertness if you find that the drug has this effect on you.

Do not take Anaprox for more than 10 days for pain or 3 days for fever. Contact your doctor if pain or fever persists or gets worse, if the painful area becomes red or swollen, or if you develop more than a mild digestive upset.